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Top cochrane.org News

Immune checkpoint inhibitors for advanced oesophageal cancer treated with surgery, radiotherapy or chemotherapy
Cancer

Immune checkpoint inhibitors for advanced oesophageal cancer treated with surgery, radiotherapy or chemotherapy

Immune checkpoint inhibitors for advanced oesophageal cancer treated with surgery, radiotherapy or chemotherapy This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To evaluate the effectiveness and safety of immune checkpoint inhibitors (ICIs) for people with advanced, unresectable or metastatic oesophageal cancer. This is a protocol....Read Article
What are the benefits and risks of different treatments for central serous chorioretinopathy (CSC)?

What are the benefits and risks of different treatments for central serous chorioretinopathy (CSC)?

What are the benefits and risks of different treatments for central serous chorioretinopathy (CSC)? Key messages - No intervention was shown to perform better for the treatment of central serous chorioretinopathy (CSC) than another. - Larger and higher-quality studies are needed to assess the benefits and potential harms of treatments for CSC. What is central serous chorioretinopathy (CSC) and how is it treated? CSC is a disorder of the back of …Read Article
What are the benefits and risks of different ways of accessing the hip joint during partial hip replacement surgery?

What are the benefits and risks of different ways of accessing the hip joint during partial hip replacement surgery?

What are the benefits and risks of different ways of accessing the hip joint during partial hip replacement surgery? Key messages The evidence is still developing, and future studies may change our conclusions. We are not confident that one surgical approach (way of accessing the hip joint) compared to another leads to a different outcome for performing daily tasks, health-related quality of life, mobility or functional status, mortality, or pai…Read Article

Are Antiplatelet Treatments or Anticoagulation Treatments Better for People Who Have Heart Failure with a Normal Heart Rhythm?

Are antiplatelet treatments or anticoagulation treatments better for people who have heart failure with a normal heart rhythm? Key messages – For people who have heart failure with a normal heart rhythm, there seems to be little to no advantage of warfarin (an anticoagulant: a medicine which prevents blood clotting by blocking proteins) over antiplatelet medicines like aspirin (which prevent blood clotting by blocking platelets). – Treatment wit…Medical · LleidaSee the Story

Do dietary and activity strategies help prevent obesity in children aged 2 to 4 years?

Do dietary and activity strategies help prevent obesity in children aged 2 to 4 years? Key messages Combining strategies for changing diet and physical activity levels in children aged 2 to 4 years to help prevent overweight and obesity may reduce body mass index (BMI) slightly in the long term (after 15 months). There was very little information about whether the strategies resulted in serious adverse events (e.g. injuries), but none of the str…ObesityRead Article

Are progestogen medications beneficial for preventing recurrent miscarriage?

Are progestogen medications beneficial for preventing recurrent miscarriage? Key messages Giving progestogen medication likely makes little to no difference to the chances of miscarriage or live birth for women who have previously had miscarriages for no known reason. What is recurrent miscarriage? Early pregnancy loss, also known as miscarriage, generally occurs in the first trimester (the first 13 weeks of pregnancy). For some women and their …Read Article

Does using multiple tests in combination ('parallel testing') result in better accuracy for detecting TB in the lungs (pulmonary tuberculosis) in children than using a single test?

Does using multiple tests in combination ('parallel testing') result in better accuracy for detecting TB in the lungs (pulmonary tuberculosis) in children than using a single test? Key messages - Using both respiratory samples and stool for low-complexity automated testing (LC-aNAATs) increased the number of pulmonary tuberculosis cases detected in children (with and without HIV). - Adding the lateral flow urine lipoarabinomannan test (LF-LAM) i…HIVRead Article

Do programs with multiple behavioral components improve the regular usage of eye pressure-lowering medications in people with glaucoma?

Do programs with multiple behavioral components improve the regular usage of eye pressure-lowering medications in people with glaucoma? Key messages Multifaceted behavioral programs that are intended to improve regular usage of eye pressure-lowering eye drops in people with high eye pressure or diagnosed with glaucoma can include a combination of reminders, multimedia education, in-person education, dosing aids, mindfulness-based stress reductio…EducationRead Article

Is obesity an endometrial cancer risk?

Last Updated on June 10, 2025 by Dr Neha Singh Obesity means having too much body fat, and it affects your overall health. Cancer that begins in the uterine lining is known as endometrial cancer. Most people are unaware that these two conditions are closely linked. In this article, we will explore the link between […] The post Is obesity an endometrial cancer risk? appeared first on THIP Media.ObesitySee the Story

In adults and adolescents with HIV, is using two different rapid tests together ('parallel testing') to diagnose tuberculosis (TB) disease more accurate than using only one?

In adults and adolescents with HIV, is using two different rapid tests together ('parallel testing') to diagnose tuberculosis (TB) disease more accurate than using only one? This review looked at adults and adolescents with HIV who have signs and symptoms of tuberculosis (TB) disease. Diagnosis can be done using respiratory samples (fluids or mucus collected by coughing or using tubes to remove fluid from the throat, lungs, or stomach) or urine.…HIVRead Article

Gonadotropin-releasing hormone (GnRH) analogues for treating premenstrual syndrome (PMS)

Gonadotropin-releasing hormone (GnRH) analogues for treating premenstrual syndrome (PMS) Review question What are the benefits and risks of using medication known as gonadotropin-releasing hormone (GnRH) agonists and antagonists in the management of premenstrual syndrome (PMS)? Key messages • We found reliable evidence that GnRH agonists without add-back improve PMS symptoms compared to placebo, but also that menopausal side effects are common, …Read Article

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