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Top Endpoints News News

HHS cancels nearly $600 million Moderna contract on vaccines for flu pandemics

Moderna · United States

HHS cancels nearly $600 million Moderna contract on vaccines for flu pandemics

65% Center coverage: 248 sources

The Department of Health and Human Services has notified Moderna that it is canceling a nearly $600 million contract with the company to develop, test, and license vaccines for flu strains that could trigger future pandemics, including the dangerous H5N1 bird flu virus. See the Story

FDA approves Moderna’s new lower-dose COVID-19 vaccine

FDA · United States

FDA approves Moderna’s new lower-dose COVID-19 vaccine

59% Center coverage: 129 sources

US court won't lift judge's block on Trump's government overhaul

US Politics · United States

US court won't lift judge's block on Trump's government overhaul

64% Center coverage: 122 sources

A U.S. appeals court on Friday refused to pause a judge's ruling blocking President Donald Trump's administration from carrying out mass layoffs of federal workers and a restructuring of government agencies as part of a sweeping government overhaul.See the Story

New three-drug combination could help women with aggressive breast cancer live longer, study suggests

57% Center coverage: 7 sources

NHS · United Kingdom See the Story

Gilead's Trodelvy, with Keytruda, cuts breast cancer risk by 35% in trial

70% Center coverage: 17 sources

Gilead Sciences´ Trodelvy in combination with Merck's blockbuster immunotherapy Keytruda lowered the risk of an aggressive type of breast cancer worsening by 35% when used as an initial treatment, according to results of a large trial presented on Saturday. The data is likely to change how patients are treated following a diagnosis for advanced triple-negative breast cancer, one expert said.Breast Cancer · United States See the Story

Korean startup Curogen seeks global expansion, new funding to back autoimmune drugs

A South Korean biotech working on multi-specific autoimmune disease treatments is looking to make a leap into the US. Curogen, based in Seoul and backed by local investors, announced Monday that it plans to open ...Seoul · Seoul See the Story

Phase 3 or bust: Why Lilly won't run mid-stage cancer trials

CHICAGO — Self-described “blunt pharma executives” Jake Van Naarden and David Hyman of Eli Lilly sat down Sunday with Endpoints News at the annual ASCO conference. The biggest takeaway from a conversation with the Indianapolis ...Eli Lilly · Indianapolis See the Story

ADC-Pertuzumab Promising as New Standard in HER2-Positive Metastatic Breast Cancer

100% Center coverage: 2 sources

(MedPage Today) -- CHICAGO -- First-line trastuzumab deruxtecan (T-DXd) combined with pertuzumab (Perjeta) improved progression-free survival (PFS) in HER2-positive locally advanced or metastatic breast cancer, according to the DESTINY-Breast09...Breast Cancer See the Story

Kymera Reports Early-Stage Success for Drug Meant to Rival Sanofi and Regeneron’s Dupixent

100% Center coverage: 1 sources

A new study finds preliminary signs the therapy might tamp down a class of immune signals linked with chronic conditions.Cambridge, Massachusetts · Cambridge See the Story

Vera Drug Scores in Closely Watched Study in Rare Kidney Disease

100% Center coverage: 2 sources

Phase 3 results revealed Monday led shares to surge and should yield an approval application in IgA nephropathy, a competitive corner of drug research, later this year.Innovation See the Story

ASCO 25: AZ Pitches Upfront Oral SERD Use in Breast Cancer

100% Center coverage: 1 sources

AstraZeneca stakes a claim to first-line treatment of HR+ breast cancer with its oral SERD, as Arvinas/Pfizer reveal their second-line dataBreast Cancer See the Story

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